TAYLOR DISPERSION ANALYZERS (TDA)
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Next-Generation Orthogonal Nanoparticle Sizing & Stability Analysis
Traditional light-scattering methods often struggle with complex, polydisperse samples or ultra-small particles in high-concentration buffers. Taylor Dispersion Analysis (TDA) provides a robust, flow-based alternative. By measuring the broadening of a sample plug injected into a laminar flow, TDA provides an absolute measurement of the hydrodynamic radius (Rh) without being affected by sample opacity, fluorescence, or large aggregate interference.
Feature & Application
- True Size Distribution: Resolve multiple populations in a single sample with high resolution.
- Native State Analysis: Measure samples directly in complex buffers, including those containing surfactants or high concentrations of salt.
- Low Sample Volume: Requires only nanoliters of sample, ideal for precious early-stage R&D.
- Micro-Viscosity: Simultaneously determine the viscosity of your formulation.
- Applications: Perfect for LNPs, AAVs, Monoclonal Antibodies (mAbs), Quantum Dots, and Polymer Micelles.
The Gold Standard for Size Distribution of Ultra-Small Nano-objects
TaylorSizer™
The TaylorSizer™ leverages Size-Distribution Taylor Dispersion Analysis (SD-TDA) to deliver unprecedented insights into samples ranging from 0.5 nm to 500 nm. Unlike DLS, the TaylorSizer™ is mass-weighted, meaning it isn’t “blinded” by a few large dust particles or aggregates, allowing you to see your primary product with crystal clarity.
